abstract：OBJECTIVES:To test the hypothesis that the hemodynamic and left ventricular functional actions of levosimendan (Orion Pharmaceutica, Espoo, Finland), a new myofilament calcium sensitizer with phosphodiesterase-inhibiting properties, in conscious dogs are correlated with plasma concentrations of the drug measured with r...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： McGough MF,Pagel PS,Lowe D,Hettrick DA,Kersten JR,Warltier DC

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:Pulmonary resection may be associated with considerable alterations of the cardiorespiratory system. The ideal anesthetic regimen for these patients is not yet definitely determined. DESIGN:Prospective, randomized study. SETTING:Single-institutional, clinical investigation in a thoracic anesthesia departmen...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Boldt J,Müller M,Uphus D,Padberg W,Hempelmann G

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVES:The present study was designed to evaluate the effects of the nitric oxide synthesis inhibitor NG-nitro-L-arginine methyl ester (L-NAME) on right ventricular (RV) contractility, both pulsatile and nonpulsatile contributions to afterload, and relate any changes to alterations in performance of the RV as a pum...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Heerdt PM,Pleimann BE

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:It has been demonstrated that new regional wall motion abnormalities (RWMAs) are infrequently associated with electrocardiographic (ECG) ischemic changes during coronary artery bypass graft (CABG) surgery. The evaluation of apical or basal areas by biplane transesophageal echocardiography (TEE) may clarify t...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Koide Y,Keehn L,Nomura T,Long T,Oka Y

更新日期：1996-10-01 00:00:00

abstract：STUDY OBJECTIVE:Cardiac surgery is complicated by decreased postoperative respiratory muscle strength and spirometry with accompanying increased atelectasis. The specific respiratory symptoms attributable to these physiologic changes are unknown, and this study looked at the symptoms and underlying physiology. DESIGN:...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Johnson D,Hurst T,Thomson D,Mycyk T,Burbridge B,To T,Mayers I

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:The central sympatholytic effects of alpha2-adrenergic agonists are believed to be beneficial during myocardial ischemia, but the peripheral vasoconstrictive effects are controversial. The aim of this study was to investigate the coronary vascular effects of dexmedetomidine (DM) during reactive hyperemia. DE...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Roekaerts PM,Prinzen FW,de Lange S

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:It was hypothesized that methylene blue could neutralize heparin in patients after cardiopulmonary bypass and become an alternative to protamine. DESIGN:This was a prospective unblinded study with patients serving as their own controls. SETTING PARTICIPANTS: A single, large university hospital. This study wa...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Metz S,Horrow JC,Goel IP,Kuretu ML,Bellwoar C

更新日期：1996-06-01 00:00:00

abstract：:These cases illustrate the advantages of the laryngeal mask as compared with an endotracheal tube or oxygen face mask for selected patients undergoing therapeutic bronchoscopic procedures. The advantages include a larger internal diameter allowing easier passage of instruments, reduced work of breathing, lack of disco...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Birmingham B,Mentzer SJ,Body SC

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:To determine the effect of cardiopulmonary bypass (CPB) on hepatic blood flow (HBF) and the hepatic venous flow pattern. DESIGN:Single-arm prospective study. SETTING:University hospital operating room and intensive care unit. PARTICIPANTS:Eight patients ranging in age from 57 to 73 years undergoing cardiac...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Gårdebäck M,Settergren G,Brodin LA

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:To compare measurements of regional myocardial blood flow volume between microsphere measurement of regional flow (0.5- to 2- g tissue sampling) and a potential alternative measure, local flow (1 mm3) in the microcirculation measured by laser-Doppler perfusion monitor. DESIGN:Prospective, randomized, control...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Sidi A,Rush W

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVES:Although volatile anesthetics have been shown to have spasmolytic effects on constricted airways, most previous studies were performed to assess bronchodilation with indirect methods such as measurement of airway resistance, whose reliability is controversial. As the authors have developed a new direct metho...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Hashimoto Y,Hirota K,Ohtomo N,Ishihara H,Matsuki A

更新日期：1996-02-01 00:00:00

abstract：:Since DeBakey's replacement of an aortic arch aneurysm using cardiopulmonary bypass and individual perfusion of the brachiocephalic and carotid arteries, selective cerebral perfusion has been used as an effective method of cerebral protection. Although interest in this technique waned with the evolution of hypothermic...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Chanyi S

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVES:Recent studies have demonstrated that perioperative myocardial ischemia, detected by electrocardiography, is a risk factor for myocardial infarction. ST-segment analyzers and hemodynamic monitors may be useful for on-line detection in perioperative and critical care environments. However, independent perform...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： London MJ,Ahlstrom LD

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVES:Several substances may be released from ischemic tissues with the declamping shock that occurs during abdominal aortic aneurysm surgery. To clarify the relationship between tissue ischemia and venous endothelin-1 (ET-1) level in humans, plasma ET-1 and oxygen content in the iliac vein were measured before an...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Fukuda S,Taga K,Tanaka T,Sakuma K,Fujiwara N,Shimoji K,Fujihara H

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:Continuous thermodilution cardiac output (CCO) measurement was clinically evaluated in patients who underwent coronary revascularization using hypothermic low-flow, low-pressure cardiopulmonary bypass (CPB). DESIGN:Prospective study. SETTING:University hospital setting. PARTICIPANTS:30 cardiac surgical pat...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Böttiger BW,Rauch H,Böhrer H,Motsch J,Soder M,Fleischer F,Martin E

更新日期：1995-08-01 00:00:00

abstract：:The recurrent or new trends of early extubation after cardiac surgery are here to stay in the 1990s. The preoperative status does not necessarily predict the postoperative course and prolonged mechanical ventilation following cardiac surgery should not be uncritically considered as routine. All patients should be asse...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Cheng DC

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVES:To determine whether amrinone is bound to cardiopulmonary bypass circuits. When amrinone is administered to children during cardiopulmonary bypass, determine whether measured amrinone concentrations differ from those predicted based on a reported volume of distribution of 1.6 L/kg. DESIGN:In vitro study: Up...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Williams GD,Sorensen GK,Oakes R,Boggs DP,Mulroy JJ Jr,Lynn AM

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:To study the influence of preoperative warfarin anticoagulation on postoperative blood loss and allogeneic blood requirement. DESIGN:Retrospective study with a matched control group. SETTING:University and community hospital, single institutional. PARTICIPANTS:240 patients scheduled for cardiac surgery. I...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Dietrich W,Dilthey G,Spannagl M,Richter JA

更新日期：1995-06-01 00:00:00

abstract：:Inadvertent postoperative hypothermia in the cardiac surgical patient can have various adverse physiologic effects. Previous studies have investigated the relationship of patient, surgical, and anesthetic factors with postoperative hypothermia in patients undergoing noncardiac surgery. This study was designed to asses...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Baker J,Baker AJ,Mazer CD

更新日期：1995-04-01 00:00:00

abstract：:To avoid intraoperative awareness and postoperative respiratory depression from high-dose opioid anesthesia, propofol (P), or isoflurane (I) has been combined with moderate-dose opioid with varying results. However, the effects of both P and I on myocardial contractility and left ventricular afterload have not been co...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Sorbara C,Pittarello D,Rizzoli G,Pasini L,Armellin G,Bonato R,Giron GP

更新日期：1995-02-01 00:00:00

abstract：:A pulmonary artery catheter (PAC) capable of continuous cardiac output (CCO) determination by thermodilution has recently been introduced. The purpose of this study was to compare CCO with two other methods of cardiac output (Ot) determination: electromagnetometry (EM) and standard bolus thermodilution cardiac output ...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Hogue CW Jr,Rosenbloom M,McCawley C,Lappas DG

更新日期：1994-12-01 00:00:00

abstract：:Patients with abdominal aortic aneurysms (AAA) have a high incidence of associated cardiac disease. If a patient presents with both severe coronary artery disease and a large AAA, a staged procedure of cardiac surgery (CS) followed by AAA resection may present too great a risk of aneurysm rupture and death. A combined...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： O'Connor MS,Licina MG,Kraenzler EJ,Savage RM,Padua-Shannon N,Starr NJ

更新日期：1994-10-01 00:00:00

abstract：:Aprotinin has been reported to reduce bleeding in cardiac surgery patients. Its mechanisms of action on coagulation have not been fully elucidated. In a prospectively randomized study of 40 patients undergoing elective aortocoronary bypass grafting, the influence of high-dose aprotinin (2 million IU of aprotinin befor...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Boldt J,Schindler E,Knothe C,Hammermann H,Stertmann WA,Hempelmann G

更新日期：1994-10-01 00:00:00

abstract：:Sotalol is a beta-adrenergic blocking drug with the additional property of lengthening the cardiac action potential. These electrophysiologic properties render the drug attractive for use in the prevention of postoperative supraventricular arrhythmias (SVA), and previous studies have suggested that it was indeed effec...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Jacquet L,Evenepoel M,Marenne F,Evrard P,Verhelst R,Dion R,Goenen M

更新日期：1994-08-01 00:00:00

abstract：:Twenty-three informed and consenting patients scheduled for CABG were anesthetized using computer-controlled infusions of alfentanil, midazolam, and pancuronium. Thirteen middle-aged patients received a preprogrammed infusion scheme of alfentanil, simulated using the population pharmacokinetic set of Maitre et al (Gro...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Barvais L,D'Hollander A,Schmartz D,Hendrice C,Cantraine F,Coussaert E

更新日期：1994-06-01 00:00:00

abstract：:To determine the effect of 1.5 MAC of two volatile anesthetics (halothane and isoflurane) on platelet-induced contraction of canine coronary artery, isolated, denuded coronary rings were suspended between two stirrups, placed into organ chambers filled with an oxygenated Krebs-Ringer solution, and connected to an isom...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Blaise GA,Parent M,Laurin S,Omri A,Reader TA,Moutquin JM

更新日期：1994-04-01 00:00:00

abstract：:The ASA Closed Claims Project has generated a standardized collection of case summaries of adverse anesthetic outcomes, with the objectives of identifying major areas of anesthesiologist liability and the contribution of substandard care to anesthetic injury. Seventy-six (3%) of the files in the project's current data...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Gild WM

更新日期：1994-02-01 00:00:00

abstract：:The mechanisms leading to left ventricular (LV) asynchronies are incompletely understood, and reports on the functional significance of asynchronies for the affected segments are conflicting. To characterize LV asynchronies, 16 anesthetized dogs with critical stenosis of the left anterior descending coronary artery (L...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Spahn DR,Hu WC,Smith LR,Leone BJ

更新日期：1993-12-01 00:00:00

abstract：:The efficacy of interpleural administration of sufentanil, 50 micrograms, was compared with that of 150 mg of bupivacaine, 0.5%, with epinephrine, 5 micrograms/mL, or saline, in 30 patients (N = 10 in each group) undergoing lateral thoracotomy. Sufentanil, bupivacaine, or saline was administered interpleurally after i...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Haak-van der Lely F,van Kleef JW,Burm AG,Bovill JG

更新日期：1993-10-01 00:00:00

abstract：:During the insertion of an automatic implantable cardioverter defibrillator, repeated induction of ventricular tachycardia or ventricular fibrillation and subsequent defibrillation is performed to determine the defibrillation threshold. In this study, the influence of these testing episodes on myocardial function was ...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Keyl C,Tassani P,Kemkes B,Markewitz A,Hoffman E,Steinbeck G

更新日期：1993-08-01 00:00:00

abstract：:Although a wide variety of positive inotropic agents have been administered to cardiac surgery patients, few of them have been carefully studied in controlled clinical trials, in surgical patient populations. The limited data available suggest that one of the more widely used agents, calcium, may lack efficacy and pos...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Butterworth J

更新日期：1993-08-01 00:00:00

abstract：:Perioperative myocardial ischemia was evaluated in 36 consecutive carotid endarterectomy procedures carried out on patients with a high (72.2%) prevalence of ischemic heart disease. The procedures were performed under cervical plexus block plus a prophylactic intravenous nitroglycerin infusion. Findings of myocardial ...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Landesberg G,Erel J,Anner H,Eidelman LA,Weinmann E,Luria MH,Admon D,Assaf J,Sapoznikov D,Berlatzky Y

更新日期：1993-06-01 00:00:00

abstract：:Nine NYHA class III-IV patients awaiting heart transplantation (HTx) were studied with a right ventricular ejection fraction (RVEF) catheter. The first aim of the study was to explore the pulmonary and systemic circulatory effects of dobutamine (D) and/or nitroprusside (N) in these patients. The second aim was to sear...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Coddens J,Delooft T,Vandenbroucke G

更新日期：1993-06-01 00:00:00

abstract：:Sixteen patients (aged 59 +/- 14 years) undergoing coronary artery bypass surgery were evaluated to delineate the intraoperative course of transesophageal echocardiographic right ventricular (RV) systolic performance indices. Pre-induction data included thermodilution RV ejection fraction (RVEFTD), 0.43 +/- 0.13, RV e...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Rafferty T,Durkin M,Harris S,Elefteriades J,Hines R,Prokop E,O'Connor T

更新日期：1993-04-01 00:00:00

abstract：:Propofol has previously been found to decrease hematocrit values. Because hematocrit is an important determinant of blood viscosity, lower hematocrits may cause a decrease in blood viscosity, improving blood flow and oxygen delivery. This phenomenon may be beneficial in certain intraoperative situations. To study the ...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Mokken FC,Henny CP,Gelb AW,Biervliet JD,Hardeman MR,Kedaria M,van Wezel HB

更新日期：1993-02-01 00:00:00

abstract：:This study investigated whether the prophylactic administration of methylprednisolone sodium succinate (MPSS) could prevent an increase in plasma endotoxin levels during cardiac surgery with cardiopulmonary bypass. MPSS (1 g/patient) or saline was given intravenously with induction in the steroid (n = 6) and control (...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Karlstad MD,Patteson SK,Guszcza JA,Langdon R,Chesney JT

更新日期：1993-02-01 00:00:00

abstract：:This study investigated the feasibility of transmyocardially pacing the heart using one temporary epicardial pacing lead and one endocardial lead of a pacing pulmonary artery catheter. Twenty patients undergoing cardiopulmonary bypass with cardioplegic arrest were studied 10 to 45 minutes and 18 to 30 hours after disc...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Roth JV

更新日期：1992-12-01 00:00:00

abstract：:The presence of an inotropic action of prostaglandin E1 (PGE1) in vivo is controversial, and there are conflicting results obtained by various indices of myocardial contractility. In this study, a direct effect of PGE1 on contractility was investigated in dogs by use of a load-independent contractile index: left ventr...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Kikura M,Ikeda T,Kazama T,Ikeda K

更新日期：1992-10-01 00:00:00

abstract：:The effects of induction of anesthesia with fentanyl, 62.1 +/- 7.9 micrograms/kg, diazepam, 0.21 +/- 0.08 mg/kg, and pancuronium on beat-to-beat heart rate variations were studied in seven patients undergoing cardiac surgery. Spectral analysis was used to determine the intensity of the variations in each of the two ma...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Komatsu T,Kimura T,Sanchala V,Shibutani K,Shimada Y

更新日期：1992-08-01 00:00:00

abstract：:Fiberoptic pulmonary artery flotation catheters have gained clinical acceptance for continuous monitoring of mixed venous oxygen saturation (SvO2), especially in the management of hemodynamically unstable patients. Therefore, the performance of the oximetry system used is extremely important. The accuracy and stabilit...

journal_title：Journal of cardiothoracic and vascular anesthesia

authors： Pond CG,Blessios G,Bowlin J,McCawley C,Lappas DG

更新日期：1992-06-01 00:00:00